Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.5
USERS' SCORE
Good
Based on 20 Reviews
8.1
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Lactoferrin (as Apolactoferrin)
250 mg
†
Top Medical Research Studies
9
We examined how KRDS, a peptide derived from human lactotransferrin, impacts platelet function and blood clot formation in dogs. The study demonstrated that KRDS effectively inhibited platelet aggregation and secretion, making it a powerful agent against clot formation.
During the experiment, KRDS reduced the weight of blood clots formed in the arteries by half compared to control groups, indicating its potential as an antithrombotic treatment. The findings suggest that KRDS may be a promising option for preventing harmful blood clots.
During the experiment, KRDS reduced the weight of blood clots formed in the arteries by half compared to control groups, indicating its potential as an antithrombotic treatment. The findings suggest that KRDS may be a promising option for preventing harmful blood clots.
Read More
9
We examined the effects of a specific lactoferrin peptide, KRDS, on blood clots compared to another peptide, RGDS. In controlled studies using rats and guinea pigs, we observed that KRDS significantly reduced platelet aggregation, showcasing its potential as an antithrombotic agent. Both in vitro and in vivo tests demonstrated that KRDS's impact was much stronger than another sequence, KRDR, which showed minimal effects on clot formation. This suggests that KRDS could play a vital role in preventing blood clots, with mechanisms that are distinct from RGDS.
Read More
8
We examined the effects of a peptide derived from lactoferrin, known as LF-LR, on blood clotting by targeting thrombin, a key factor in thrombosis. In our investigation, LF-LR significantly delayed various coagulation times, indicating its potential to hinder blood clot formation.
By altering thrombin's structure, LF-LR transformed its secondary forms, enhancing its functionality in anticoagulation. Molecular docking studies revealed that this peptide attaches to thrombin at critical sites, strengthening its role as an anticoagulant. These findings suggest that lactoferrin may be an interesting area for future research in blood clot management.
By altering thrombin's structure, LF-LR transformed its secondary forms, enhancing its functionality in anticoagulation. Molecular docking studies revealed that this peptide attaches to thrombin at critical sites, strengthening its role as an anticoagulant. These findings suggest that lactoferrin may be an interesting area for future research in blood clot management.
Read More
Most Useful Reviews
9
Hair loss halted
64 people found this helpful
This product significantly stopped my hair loss due to iron deficiency anaemia, which caused brittle nails and skin dryness. Traditional iron supplements yielded no results, but I found that lactoferrin enhances iron absorption. After two months, my iron levels normalised, my overall health improved, my skin is no longer dry, and hair loss ceased almost entirely. The package lasts for two months with one capsule daily, and I hope my experience aids others facing similar challenges!
Read More
9
Effective, recommended product
34 people found this helpful
I took this alongside Solaray iron due to my low ferritin (27) after severe blood loss from childbirth. Over 1.5 months, it raised my ferritin to 70. No other iron supplement compares! I highly recommend it and it caused no gastrointestinal issues, unlike many iron products.
Read More
7.5
Significant blood improvement
5 people found this helpful
These capsules are excellent for combating anaemia. I noticed substantial benefits during my last blood test, with improved iron retention and an enhanced haemoglobin count. My doctor prescribes one capsule in the morning and one in the evening for two months, alongside iron. The capsules are tasteless, easy to swallow, and gentle on my stomach, indicating the high quality of the ingredients.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.5
- All Researches
9
We examined how KRDS, a peptide derived from human lactotransferrin, impacts platelet function and blood clot formation in dogs. The study demonstrated that KRDS effectively inhibited platelet aggregation and secretion, making it a powerful agent against clot formation.
During the experiment, KRDS reduced the weight of blood clots formed in the arteries by half compared to control groups, indicating its potential as an antithrombotic treatment. The findings suggest that KRDS may be a promising option for preventing harmful blood clots.
During the experiment, KRDS reduced the weight of blood clots formed in the arteries by half compared to control groups, indicating its potential as an antithrombotic treatment. The findings suggest that KRDS may be a promising option for preventing harmful blood clots.
Read More
9
We examined the effects of a specific lactoferrin peptide, KRDS, on blood clots compared to another peptide, RGDS. In controlled studies using rats and guinea pigs, we observed that KRDS significantly reduced platelet aggregation, showcasing its potential as an antithrombotic agent. Both in vitro and in vivo tests demonstrated that KRDS's impact was much stronger than another sequence, KRDR, which showed minimal effects on clot formation. This suggests that KRDS could play a vital role in preventing blood clots, with mechanisms that are distinct from RGDS.
Read More
8
We examined the effects of a peptide derived from lactoferrin, known as LF-LR, on blood clotting by targeting thrombin, a key factor in thrombosis. In our investigation, LF-LR significantly delayed various coagulation times, indicating its potential to hinder blood clot formation.
By altering thrombin's structure, LF-LR transformed its secondary forms, enhancing its functionality in anticoagulation. Molecular docking studies revealed that this peptide attaches to thrombin at critical sites, strengthening its role as an anticoagulant. These findings suggest that lactoferrin may be an interesting area for future research in blood clot management.
By altering thrombin's structure, LF-LR transformed its secondary forms, enhancing its functionality in anticoagulation. Molecular docking studies revealed that this peptide attaches to thrombin at critical sites, strengthening its role as an anticoagulant. These findings suggest that lactoferrin may be an interesting area for future research in blood clot management.
Read More
8
We explored the effects of lactoferrin on neutrophil extracellular traps (NETs), which play a role in both defense and the formation of harmful blood clots. Our findings indicate that lactoferrin suppresses the release of NETs in the bloodstream, reducing potential clot formation in inflammatory conditions. This suppression may hinge on lactoferrin's positive charge interacting with NETs, as removing this charge diminished its effectiveness. Although these results are promising for using lactoferrin in treating autoimmune and inflammatory diseases, they reveal no immediate benefits for directly preventing blood clots.
Read More
User Reviews
USERS' SCORE
Good
Based on 20 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Hair loss halted
64 people found this helpful
This product significantly stopped my hair loss due to iron deficiency anaemia, which caused brittle nails and skin dryness. Traditional iron supplements yielded no results, but I found that lactoferrin enhances iron absorption. After two months, my iron levels normalised, my overall health improved, my skin is no longer dry, and hair loss ceased almost entirely. The package lasts for two months with one capsule daily, and I hope my experience aids others facing similar challenges!
Read More
9
Effective, recommended product
34 people found this helpful
I took this alongside Solaray iron due to my low ferritin (27) after severe blood loss from childbirth. Over 1.5 months, it raised my ferritin to 70. No other iron supplement compares! I highly recommend it and it caused no gastrointestinal issues, unlike many iron products.
Read More
7.5
Significant blood improvement
5 people found this helpful
These capsules are excellent for combating anaemia. I noticed substantial benefits during my last blood test, with improved iron retention and an enhanced haemoglobin count. My doctor prescribes one capsule in the morning and one in the evening for two months, alongside iron. The capsules are tasteless, easy to swallow, and gentle on my stomach, indicating the high quality of the ingredients.
Read More
10
Improved iron levels
2 people found this helpful
This perfectly raises iron levels in the blood! According to the tests, my ferritin has increased threefold! I recommend it.
Read More
9
Boosted limb vitality
2 people found this helpful
I purchased lactoferrin repeatedly from iHerb, recommended by my chiropractor for alleviating heavy sensations in my limbs. My doctor hesitated to test for hemochromatosis, and donating blood isn't an option for me. This product has significantly eased my discomfort! Though I need to budget for it, it's worthwhile. The dosage works well for me, and I have not experienced adverse reactions.
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Frequently Asked Questions
9
Significant increase
I took it for just one month, and it significantly increased my iron and ferritin levels in my blood. My ferritin went from 11 to 80, and my iron also rose from the lower limit to the upper limit.
9
Hair loss halted
64 people found this helpful
This product significantly stopped my hair loss due to iron deficiency anaemia, which caused brittle nails and skin dryness. Traditional iron supplements yielded no results, but I found that lactoferrin enhances iron absorption. After two months, my iron levels normalised, my overall health improved, my skin is no longer dry, and hair loss ceased almost entirely. The package lasts for two months with one capsule daily, and I hope my experience aids others facing similar challenges!
2
Costs outweigh benefits
3 people found this helpful
Lactoferrin is claimed to raise blood ferritin and haemoglobin levels. However, I found it ineffective for me. Given the price, I would recommend opting for high-quality iron supplements instead.
9
Effective, recommended product
34 people found this helpful
I took this alongside Solaray iron due to my low ferritin (27) after severe blood loss from childbirth. Over 1.5 months, it raised my ferritin to 70. No other iron supplement compares! I highly recommend it and it caused no gastrointestinal issues, unlike many iron products.
7.5
Significant blood improvement
5 people found this helpful
These capsules are excellent for combating anaemia. I noticed substantial benefits during my last blood test, with improved iron retention and an enhanced haemoglobin count. My doctor prescribes one capsule in the morning and one in the evening for two months, alongside iron. The capsules are tasteless, easy to swallow, and gentle on my stomach, indicating the high quality of the ingredients.
9
Improved fatigue quickly
1 people found this helpful
For years, I struggled with extreme fatigue due to chronic disease/inflammation-related anaemia. Within days of beginning lactoferrin, I felt improvements without needing iron supplements. Caution is necessary with iron if your ferritin is already high. There is now hope for me!
3
Not suitable for anemia
2 people found this helpful
Good product. It can be useful in cases of bacterial infections, but you must be cautious! If you suffer from anaemia, apolactoferrin (lactoferrin without iron) can worsen your situation. After two months of taking this supplement, I had to stop because my blood ferritin levels dropped significantly. It may have helped inhibit the growth of pathogens, but I ended up with low iron. I believe in its effectiveness, but it didn't suit me, or rather, it had too noticeable a side effect on my body. I wouldn’t recommend it to anyone with iron deficiencies.
9
Boosted ferritin level
17 people found this helpful
I believe that this supplement well boosted my ferritin levels. I took it with iron at night. After finishing the iron, I will finish another jar of lactoferrin. Then, I plan to take iron with lactoferrin once a month for 5-7 days during periods of blood loss.
9
We examined how KRDS, a peptide derived from human lactotransferrin, impacts platelet function and blood clot formation in dogs. The study demonstrated that KRDS effectively inhibited platelet aggregation and secretion, making it a powerful agent against clot formation.
During the experiment, KRDS reduced the weight of blood clots formed in the arteries by half compared to control groups, indicating its potential as an antithrombotic treatment. The findings suggest that KRDS may be a promising option for preventing harmful blood clots.
During the experiment, KRDS reduced the weight of blood clots formed in the arteries by half compared to control groups, indicating its potential as an antithrombotic treatment. The findings suggest that KRDS may be a promising option for preventing harmful blood clots.
9
We examined the effects of a specific lactoferrin peptide, KRDS, on blood clots compared to another peptide, RGDS. In controlled studies using rats and guinea pigs, we observed that KRDS significantly reduced platelet aggregation, showcasing its potential as an antithrombotic agent. Both in vitro and in vivo tests demonstrated that KRDS's impact was much stronger than another sequence, KRDR, which showed minimal effects on clot formation. This suggests that KRDS could play a vital role in preventing blood clots, with mechanisms that are distinct from RGDS.
8
We explored the effects of lactoferrin on neutrophil extracellular traps (NETs), which play a role in both defense and the formation of harmful blood clots. Our findings indicate that lactoferrin suppresses the release of NETs in the bloodstream, reducing potential clot formation in inflammatory conditions. This suppression may hinge on lactoferrin's positive charge interacting with NETs, as removing this charge diminished its effectiveness. Although these results are promising for using lactoferrin in treating autoimmune and inflammatory diseases, they reveal no immediate benefits for directly preventing blood clots.
References
- Xu S, Fan F, Liu H, Cheng S, Tu M, et al. Novel Anticoagulant Peptide from Lactoferrin Binding Thrombin at the Active Site and Exosite-I. J Agric Food Chem. 2020;68:3132. doi:10.1021/acs.jafc.9b08094
- Okubo K, Kamiya M, Urano Y, Nishi H, Herter JM, et al. Lactoferrin Suppresses Neutrophil Extracellular Traps Release in Inflammation. EBioMedicine. 2016;10:204. doi:10.1016/j.ebiom.2016.07.012
- Wu G, Ruan C, Drouet L, Caen J. Inhibition effects of KRDS, a peptide derived from lactotransferrin, on platelet function and arterial thrombus formation in dogs. Haemostasis. 1992;22:1.
- Drouet L, Bal dit Sollier C, Cisse M, Pignaud G, Mazoyer E, et al. The antithrombotic effect of KRDS, a lactotransferrin peptide, compared with RGDS. Nouv Rev Fr Hematol (1978). 1990;32:59.
